Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Medication for pain relief, constipation, heartburn__6154-both_sexes-4 |
| Phenotype | NoPhenotypeAvailable |
| Upregulated in class | na_pos |
| GeneSet | CL34187, DESMOSOME, AND ICHTHYOSIS VULGARIS |
| Enrichment Score (ES) | 0.5796702 |
| Normalized Enrichment Score (NES) | 1.1947172 |
| Nominal p-value | 0.14314315 |
| FDR q-value | 0.44922134 |
| FWER p-Value | 0.99 |
| SYMBOL | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|
| 1 | PPL | 215 | 2.130 | 0.1673 | Yes |
| 2 | DSC2 | 463 | 1.747 | 0.3006 | Yes |
| 3 | KRT1 | 1417 | 1.148 | 0.3444 | Yes |
| 4 | KRT10 | 1797 | 0.995 | 0.4071 | Yes |
| 5 | PERP | 2022 | 0.924 | 0.4724 | Yes |
| 6 | BLMH | 2469 | 0.815 | 0.5162 | Yes |
| 7 | DSC3 | 2538 | 0.799 | 0.5797 | Yes |
| 8 | DSG1 | 4360 | 0.508 | 0.5216 | No |
| 9 | DSP | 5956 | 0.375 | 0.4648 | No |
| 10 | DSG3 | 6164 | 0.360 | 0.4836 | No |
| 11 | TMEM43 | 6546 | 0.335 | 0.4907 | No |
| 12 | CASP14 | 7989 | 0.254 | 0.4322 | No |
| 13 | EVPL | 8065 | 0.250 | 0.4491 | No |
| 14 | SERPINB12 | 8654 | 0.226 | 0.4356 | No |
| 15 | CDSN | 9792 | 0.184 | 0.3881 | No |
| 16 | JUP | 10902 | 0.150 | 0.3393 | No |
| 17 | DSG2 | 12098 | 0.120 | 0.2832 | No |
| 18 | PKP1 | 12408 | 0.113 | 0.2755 | No |
| 19 | PKP2 | 12475 | 0.111 | 0.2812 | No |
| 20 | PKP3 | 12962 | 0.100 | 0.2627 | No |
| 21 | DSC1 | 14048 | 0.079 | 0.2093 | No |
| 22 | LORICRIN | 14470 | 0.072 | 0.1920 | No |
| 23 | KRT2 | 15640 | 0.052 | 0.1316 | No |
| 24 | KRT77 | 16165 | 0.043 | 0.1063 | No |
